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Human recombinant truncated RNASET2, devoid of RNase activity; A potential cancer therapeutic agent

Human RNASET2 has been implicated in antitumorigenic and antiangiogenic activities, independent of its ribonuclease capacities. We constructed a truncated version of human RNASET2, starting at E50 (trT2-50) and devoid of ribonuclease activity. trT2-50 maintained its ability to bind actin and to inhi...

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Detalles Bibliográficos
Autores principales: Nesiel-Nuttman, Liron, Schwartz, Betty, Shoseyov, Oded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294338/
https://www.ncbi.nlm.nih.gov/pubmed/25426551