Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance

Myxofibrosarcomas are genetically complex and involve recurrently deleted chromosome 9p, for which we characterized the pathogenically relevant target(s) using genomic profiling. In 12 of the 15 samples, we detected complete or partial losses of 9p. The only aggressiveness-associated, differentially...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Chien-Feng, Fang, Fu-Min, Kung, Hsing-Jien, Chen, Li-Tzong, Wang, Jun-Wen, Tsai, Jen-Wei, Yu, Shih Chen, Wang, Yu-Hui, Li, Shau-Hsuan, Huang, Hsuan-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294342/
https://www.ncbi.nlm.nih.gov/pubmed/25426549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294342/
https://www.ncbi.nlm.nih.gov/pubmed/25426549

Ejemplares similares