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Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance
Myxofibrosarcomas are genetically complex and involve recurrently deleted chromosome 9p, for which we characterized the pathogenically relevant target(s) using genomic profiling. In 12 of the 15 samples, we detected complete or partial losses of 9p. The only aggressiveness-associated, differentially...
Autores principales: | Li, Chien-Feng, Fang, Fu-Min, Kung, Hsing-Jien, Chen, Li-Tzong, Wang, Jun-Wen, Tsai, Jen-Wei, Yu, Shih Chen, Wang, Yu-Hui, Li, Shau-Hsuan, Huang, Hsuan-Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294342/ https://www.ncbi.nlm.nih.gov/pubmed/25426549 |
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