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Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer

The present study aims to investigate whether gastrokine 1 (GKN1) induces senescence and apoptosis in gastric cancer cells by regulating telomere length and telomerase activity. Telomere length, telomerase activity, and hTERT expression decreased significantly in AGS(GKN1) and MKN1(GKN1) cells. Both...

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Detalles Bibliográficos
Autores principales: Yoon, Jung Hwan, Seo, Ho Seok, Choi, Won Seok, Kim, Olga, Nam, Suk Woo, Lee, Jung Young, Park, Won Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294346/
https://www.ncbi.nlm.nih.gov/pubmed/25344918