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Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis

Glioblastoma are highly aggressive brain tumors with poor prognosis. While various dysregulation of signaling pathways in gliomas have been described, the identification of biomarkers and therapy targets remains an important task for novel diagnostic and therapeutic approaches. Here we described tha...

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Detalles Bibliográficos
Autores principales: Liu, Xing, Wang, Xiaofeng, Du, Wenzhong, Chen, Lingchao, Wang, Guangzhi, Cui, Yuqiong, Liu, Yang, Dou, Zhijin, Wang, Hongjun, Zhang, Ping, Chang, Liang, Yi, Liye, Cai, Jinquan, Jiang, Chuanlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294353/
https://www.ncbi.nlm.nih.gov/pubmed/25373737