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Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress

Unwinding duplex DNA is a critical processing step during replication, repair and transcription. Pif1 are highly conserved non-processive 5′->3′ DNA helicases with well-established roles in maintenance of yeast genome stability. However, the function of the sole member of Pif1 family in humans re...

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Detalles Bibliográficos
Autores principales: Gagou, Mary E., Ganesh, Anil, Phear, Geraldine, Robinson, Darren, Petermann, Eva, Cox, Angela, Meuth, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294361/
https://www.ncbi.nlm.nih.gov/pubmed/25359767