STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters

Retinoblastoma, the most common intraocular malignant tumor in children, is characterized by the loss of both functional alleles of RB1 gene, which however alone cannot maintain malignant characteristics of retinoblastoma cells. Nevertheless, the investigation of other molecular aberrations such as...

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Detalles Bibliográficos
Autores principales: Jo, Dong Hyun, Kim, Jin Hyoung, Cho, Chang Sik, Cho, Young-Lai, Jun, Hyoung Oh, Yu, Young Suk, Min, Jeong-Ki, Kim, Jeong Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294389/
https://www.ncbi.nlm.nih.gov/pubmed/25359779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294389/
https://www.ncbi.nlm.nih.gov/pubmed/25359779

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