CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke

While the detrimental role of non-regulatory T cells in ischemic stroke is meanwhile unequivocally recognized, there are controversies about the properties of regulatory T cells (T(reg)). The aim of this study was to elucidate the role of T(reg) by applying superagonistic anti-CD28 antibody expansio...

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Detalles Bibliográficos
Autores principales: Schuhmann, Michael K, Kraft, Peter, Stoll, Guido, Lorenz, Kristina, Meuth, Sven G, Wiendl, Heinz, Nieswandt, Bernhard, Sparwasser, Tim, Beyersdorf, Niklas, Kerkau, Thomas, Kleinschnitz, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294400/
https://www.ncbi.nlm.nih.gov/pubmed/25315859
http://dx.doi.org/10.1038/jcbfm.2014.175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294400/
https://www.ncbi.nlm.nih.gov/pubmed/25315859
http://dx.doi.org/10.1038/jcbfm.2014.175

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