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The mitochondrial permeability transition pore: Molecular nature and role as a target in cardioprotection

The mitochondrial permeability transition (PT) – an abrupt increase permeability of the inner membrane to solutes – is a causative event in ischemia–reperfusion injury of the heart, and the focus of intense research in cardioprotection. The PT is due to opening of the PT pore (PTP), a high conductan...

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Detalles Bibliográficos
Autores principales: Bernardi, Paolo, Di Lisa, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294587/
https://www.ncbi.nlm.nih.gov/pubmed/25268651
http://dx.doi.org/10.1016/j.yjmcc.2014.09.023