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The mitochondrial permeability transition pore: Molecular nature and role as a target in cardioprotection
The mitochondrial permeability transition (PT) – an abrupt increase permeability of the inner membrane to solutes – is a causative event in ischemia–reperfusion injury of the heart, and the focus of intense research in cardioprotection. The PT is due to opening of the PT pore (PTP), a high conductan...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294587/ https://www.ncbi.nlm.nih.gov/pubmed/25268651 http://dx.doi.org/10.1016/j.yjmcc.2014.09.023 |