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Stable, Metastable, and Kinetically Trapped Amyloid Aggregate Phases

[Image: see text] Self-assembly of proteins into amyloid fibrils plays a key role in a multitude of human disorders that range from Alzheimer’s disease to type II diabetes. Compact oligomeric species, observed early during amyloid formation, are reported as the molecular entities responsible for the...

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Detalles Bibliográficos
Autores principales: Miti, Tatiana, Mulaj, Mentor, Schmit, Jeremy D., Muschol, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294590/
https://www.ncbi.nlm.nih.gov/pubmed/25469942
http://dx.doi.org/10.1021/bm501521r