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Screening strategies to identify HSP70 modulators to treat Alzheimer’s disease

Alzheimer’s disease, the most common type of dementia, is a progressive brain disease that destroys cognitive function and eventually leads to death. In patients with Alzheimer’s disease, beta amyloids and tau proteins form plaques/oligomers and oligomers/tangles that affect the ability of neurons t...

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Detalles Bibliográficos
Autores principales: Repalli, Jayanthi, Meruelo, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294646/
https://www.ncbi.nlm.nih.gov/pubmed/25609918
http://dx.doi.org/10.2147/DDDT.S72165