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Sample sizes in dosage investigational clinical trials: a systematic evaluation

The main purpose of investigational phase II clinical trials is to explore indications and effective doses. However, as yet, there is no clear rule and no related published literature about the precise suitable sample sizes to be used in phase II clinical trials. To explore this, we searched for cli...

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Detalles Bibliográficos
Autores principales: Huang, Ji-Han, Su, Qian-Min, Yang, Juan, Lv, Ying-Hua, He, Ying-Chun, Chen, Jun-Chao, Xu, Ling, Wang, Kun, Zheng, Qing-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294651/
https://www.ncbi.nlm.nih.gov/pubmed/25609916
http://dx.doi.org/10.2147/DDDT.S76135