Detailed Phenotypic and Molecular Analyses of Genetically Modified Mice Generated by CRISPR-Cas9-Mediated Editing

The bacterial CRISPR-Cas9 system has been adapted for use as a genome editing tool. While several recent reports have indicated that successful genome editing of mice can be achieved, detailed phenotypic and molecular analyses of the mutant animals are limited. Following pronuclear micro-injection o...

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Detalles Bibliográficos
Autores principales: Parikh, Bijal A., Beckman, Diana L., Patel, Swapneel J., White, J. Michael, Yokoyama, Wayne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294663/
https://www.ncbi.nlm.nih.gov/pubmed/25587897
http://dx.doi.org/10.1371/journal.pone.0116484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294663/
https://www.ncbi.nlm.nih.gov/pubmed/25587897
http://dx.doi.org/10.1371/journal.pone.0116484

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