Kinetic control by limiting glutaredoxin amounts enables thiol oxidation in the reducing mitochondrial intermembrane space

The mitochondrial intermembrane space (IMS) harbors an oxidizing machinery that drives import and folding of small cysteine-containing proteins without targeting signals. The main component of this pathway is the oxidoreductase Mia40, which introduces disulfides into its substrates. We recently show...

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Detalles Bibliográficos
Autores principales: Kojer, Kerstin, Peleh, Valentina, Calabrese, Gaetano, Herrmann, Johannes M., Riemer, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294668/
https://www.ncbi.nlm.nih.gov/pubmed/25392302
http://dx.doi.org/10.1091/mbc.E14-10-1422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294668/
https://www.ncbi.nlm.nih.gov/pubmed/25392302
http://dx.doi.org/10.1091/mbc.E14-10-1422

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