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Association of the circadian factor Period 2 to p53 influences p53's function in DNA-damage signaling
Circadian period proteins influence cell division and death by associating with checkpoint components, although their mode of regulation has not been firmly established. hPer2 forms a trimeric complex with hp53 and its negative regulator Mdm2. In unstressed cells, this association leads to increased...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294682/ https://www.ncbi.nlm.nih.gov/pubmed/25411341 http://dx.doi.org/10.1091/mbc.E14-05-0994 |