Sustained signalling by PTH modulates IP(3) accumulation and IP(3) receptors through cyclic AMP junctions

Parathyroid hormone (PTH) stimulates adenylyl cyclase through type 1 PTH receptors (PTH(1)R) and potentiates the Ca(2+) signals evoked by carbachol, which stimulates formation of inositol 1,4,5-trisphosphate (IP(3)). We confirmed that in HEK cells expressing PTH(1)R, acute stimulation with PTH(1-34)...

Descripción completa

Detalles Bibliográficos
Autores principales: Meena, Abha, Tovey, Stephen C., Taylor, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294780/
https://www.ncbi.nlm.nih.gov/pubmed/25431134
http://dx.doi.org/10.1242/jcs.163071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294780/
https://www.ncbi.nlm.nih.gov/pubmed/25431134
http://dx.doi.org/10.1242/jcs.163071

Ejemplares similares