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Persistence of Anti-Desmoglein 3 IgG(+) B-Cell Clones in Pemphigus Patients Over Years

Pemphigus vulgaris (PV) is a prototypic tissue-specific autoantibody-mediated disease in which anti-desmoglein 3 (Dsg3) immunoglobulin G (IgG) autoantibodies cause life-threatening blistering. We characterized the autoimmune B-cell response over 14 patient-years in two patients with active and relap...

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Detalles Bibliográficos
Autores principales: Hammers, Christoph M., Chen, Jing, Lin, Chenyan, Kacir, Stephen, Siegel, Don L., Payne, Aimee S., Stanley, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294994/
https://www.ncbi.nlm.nih.gov/pubmed/25142730
http://dx.doi.org/10.1038/jid.2014.291