Cargando…
Persistence of Anti-Desmoglein 3 IgG(+) B-Cell Clones in Pemphigus Patients Over Years
Pemphigus vulgaris (PV) is a prototypic tissue-specific autoantibody-mediated disease in which anti-desmoglein 3 (Dsg3) immunoglobulin G (IgG) autoantibodies cause life-threatening blistering. We characterized the autoimmune B-cell response over 14 patient-years in two patients with active and relap...
Autores principales: | Hammers, Christoph M., Chen, Jing, Lin, Chenyan, Kacir, Stephen, Siegel, Don L., Payne, Aimee S., Stanley, John R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294994/ https://www.ncbi.nlm.nih.gov/pubmed/25142730 http://dx.doi.org/10.1038/jid.2014.291 |
Ejemplares similares
-
Pathogenicity and Epitope Characteristics Do Not Differ in IgG Subclass-Switched Anti-Desmoglein 3 IgG1 and IgG4 Autoantibodies in Pemphigus Vulgaris
por: Lo, Agnes S., et al.
Publicado: (2016) -
Endocytosis of IgG, Desmoglein 1, and Plakoglobin in Pemphigus Foliaceus Patient Skin
por: Oktarina, Dyah A. M., et al.
Publicado: (2019) -
Plakophilins, desmogleins, and pemphigus: the tail wagging the dog
por: Ellebrecht, Christoph T., et al.
Publicado: (2014) -
Immunoadsorption of Desmoglein-3-Specific IgG Abolishes the Blister-Inducing Capacity of Pemphigus Vulgaris IgG in Neonatal Mice
por: Hofrichter, Maxi, et al.
Publicado: (2018) -
Faster IgG4 Depletion Kinetics Observed for Anti-Desmoglein 3 Autoantibodies Following Rituximab Treatment in Patients with Pemphigus Vulgaris
por: BOCH, Katharina, et al.
Publicado: (2022)