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Fluvastatin Upregulates the α (1C) Subunit of CaV1.2 Channel Expression in Vascular Smooth Muscle Cells via RhoA and ERK/p38 MAPK Pathways

Abnormal phenotypic switch of vascular smooth muscle cell (VSMC) is a hallmark of vascular disorders such as atherosclerosis and restenosis. And this process has been related to remodeling of L-type calcium channel (LTCC). We attempted to investigate whether fluvastatin has any effect on VSMC prolif...

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Detalles Bibliográficos
Autores principales: Ouyang, Qiu-Fang, Han, Ying, Lin, Zhi-Hong, Xie, Hong, Xu, Chang-Sheng, Xie, Liang-Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295146/
https://www.ncbi.nlm.nih.gov/pubmed/25614710
http://dx.doi.org/10.1155/2014/237067