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Angelica sinensis extract inhibits RANKL-mediated osteoclastogenesis by down-regulated the expression of NFATc1 in mouse bone marrow cells

BACKGROUND: Destructive erosion of bone or osteolysis is a major complication of inflammatory conditions such as rheumatoid arthritis (RA), periodontal disease, and periprosthetic osteolysis. Natural plant-derived products have received recent attention as potential therapeutic and preventative drug...

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Detalles Bibliográficos
Autores principales: Kong, Lingbo, Zhao, Qinpeng, Wang, Xiaodong, Zhu, Jinyu, Hao, Dingjun, Yang, Chongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295400/
https://www.ncbi.nlm.nih.gov/pubmed/25496242
http://dx.doi.org/10.1186/1472-6882-14-481