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Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP
Elucidation of prion protein (PrP) functions is crucial to fully understand prion diseases. A major approach to studying PrP functions is the use of PrP gene-knockout (Prnp(−/−)) mice. So far, six types of Prnp(−/−) mice have been generated, demonstrating the promiscuous functions of PrP. Recently,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295555/ https://www.ncbi.nlm.nih.gov/pubmed/25642423 http://dx.doi.org/10.3389/fcell.2014.00075 |