PGC1α −1 Nucleosome Position and Splice Variant Expression and Cardiovascular Disease Risk in Overweight and Obese Individuals

PGC1α, a transcriptional coactivator, interacts with PPARs and others to regulate skeletal muscle metabolism. PGC1α undergoes splicing to produce several mRNA variants, with the NTPGC1α variant having a similar biological function to the full length PGC1α (FLPGC1α). CVD is associated with obesity an...

Descripción completa

Detalles Bibliográficos
Autores principales: Henagan, Tara M., Stewart, Laura K., Forney, Laura A., Sparks, Lauren M., Johannsen, Neil, Church, Timothy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295622/
https://www.ncbi.nlm.nih.gov/pubmed/25614734
http://dx.doi.org/10.1155/2014/895734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295622/
https://www.ncbi.nlm.nih.gov/pubmed/25614734
http://dx.doi.org/10.1155/2014/895734

Ejemplares similares