Modeling the influence of stromal microenvironment in the selection of ENU-induced BCR-ABL1 mutants by tyrosine kinase inhibitors

Tyrosine kinase inhibitors (TKIs) have profoundly changed the natural history of chronic myeloid leukemia (CML). However, acquired resistance to imatinib, dasatinib or nilotinib (1(st) and 2(nd) generation TKIs), due in part to BCR-ABL1 kinase mutations, has been largely described. These drugs are i...

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Detalles Bibliográficos
Autores principales: Aggoune, Djamel, Tosca, Lucie, Sorel, Nathalie, Bonnet, Marie-Laure, Dkhissi, Fatima, Tachdjian, Gérard, Bennaceur-Griscelli, Annelise, Chomel, Jean-Claude, Turhan, Ali G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295758/
https://www.ncbi.nlm.nih.gov/pubmed/25593988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295758/
https://www.ncbi.nlm.nih.gov/pubmed/25593988

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