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MET nucleotide variations and amplification in advanced ovarian cancer: characteristics and outcomes with c-Met inhibitors

PURPOSE: MET alterations including amplifications and nucleotide variations have been associated with resistance to therapy and aggressive clinical behavior. EXPERIMENTAL DESIGN: The medical records of patients presenting to the University of Texas MD Anderson Cancer Center Phase I Clinic with relap...

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Detalles Bibliográficos
Autores principales: Tang, Chad, Fontes Jardim, Denis L., Falchook, Gerald S., Hess, Kenneth, Fu, Siqing, Wheler, Jennifer J., Zinner, Ralph G., Naing, Aung, Tsimberidou, Apostolia M., De Melo Galgiato, Debora, Westin, Shannon N., Meric-Bernstam, Funda, Kurzrock, Razelle, Hong, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295762/
https://www.ncbi.nlm.nih.gov/pubmed/25593979