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GITR Intrinsically Sustains Early Type 1 and Late Follicular Helper CD4 T Cell Accumulation to Control a Chronic Viral Infection

CD4 T cells are critical for control of persistent infections; however, the key signals that regulate CD4 T help during chronic infection remain incompletely defined. While several studies have addressed the role of inhibitory receptors and soluble factors such as PD-1 and IL-10, significantly less...

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Detalles Bibliográficos
Autores principales: Clouthier, Derek L., Zhou, Angela C., Wortzman, Michael E., Luft, Olga, Levy, Gary A., Watts, Tania H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295864/
https://www.ncbi.nlm.nih.gov/pubmed/25590581
http://dx.doi.org/10.1371/journal.ppat.1004517