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GITR Intrinsically Sustains Early Type 1 and Late Follicular Helper CD4 T Cell Accumulation to Control a Chronic Viral Infection
CD4 T cells are critical for control of persistent infections; however, the key signals that regulate CD4 T help during chronic infection remain incompletely defined. While several studies have addressed the role of inhibitory receptors and soluble factors such as PD-1 and IL-10, significantly less...
Autores principales: | Clouthier, Derek L., Zhou, Angela C., Wortzman, Michael E., Luft, Olga, Levy, Gary A., Watts, Tania H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295864/ https://www.ncbi.nlm.nih.gov/pubmed/25590581 http://dx.doi.org/10.1371/journal.ppat.1004517 |
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