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Overexpression of Tau Downregulated the mRNA Levels of Kv Channels and Improved Proliferation in N2A Cells

Microtubule binding protein tau has a crucial function in promoting the assembly and stabilization of microtubule. Besides tuning the action potentials, voltage-gated K(+) channels (Kv) are important for cell proliferation and appear to play a role in the development of cancer. However, little is kn...

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Detalles Bibliográficos
Autores principales: Li, Xiantao, Hu, Ximu, Li, Xiaoqing, Hao, Xuran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295873/
https://www.ncbi.nlm.nih.gov/pubmed/25590133
http://dx.doi.org/10.1371/journal.pone.0116628