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Overexpression of Tau Downregulated the mRNA Levels of Kv Channels and Improved Proliferation in N2A Cells
Microtubule binding protein tau has a crucial function in promoting the assembly and stabilization of microtubule. Besides tuning the action potentials, voltage-gated K(+) channels (Kv) are important for cell proliferation and appear to play a role in the development of cancer. However, little is kn...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295873/ https://www.ncbi.nlm.nih.gov/pubmed/25590133 http://dx.doi.org/10.1371/journal.pone.0116628 |