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Th17 Down-regulation Is Involved in Reduced Progression of Schistosomiasis Fibrosis in ICOSL KO Mice

BACKGROUND: Granulomatous and fibrosing inflammation in response to parasite eggs is the main pathology that occurs during infection with Schistosoma spp. CD4+ T cells play critical roles in both host immune responses against parasitic infection and immunopathology in schistosomiasis,and coordinate...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Liang, Song, Wang, Yu, Zhu, Xing-Quan, Gong, Wei, Zhang, Hui-Qin, Li, Ying, Xia, Chao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295877/
https://www.ncbi.nlm.nih.gov/pubmed/25590646
http://dx.doi.org/10.1371/journal.pntd.0003434