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Distinct Cellular Calcium Metabolism in Radiation-sensitive RKO Human Colorectal Cancer Cells

Radiation therapy for variety of human solid tumors utilizes mechanism of cell death after DNA damage caused by radiation. In response to DNA damage, cytochrome c was released from mitochondria by activation of pro-apoptotic Bcl-2 family proteins, and then elicits massive Ca(2+) release from the ER...

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Detalles Bibliográficos
Autores principales: Kim, Yun Tai, Jo, Soo Shin, Park, Young Jun, Lee, Myung Za, Suh, Chang Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296041/
https://www.ncbi.nlm.nih.gov/pubmed/25598666
http://dx.doi.org/10.4196/kjpp.2014.18.6.509