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subSeq: Determining Appropriate Sequencing Depth Through Efficient Read Subsampling

Motivation: Next-generation sequencing experiments, such as RNA-Seq, play an increasingly important role in biological research. One complication is that the power and accuracy of such experiments depend substantially on the number of reads sequenced, so it is important and challenging to determine...

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Detalles Bibliográficos
Autores principales: Robinson, David G., Storey, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296149/
https://www.ncbi.nlm.nih.gov/pubmed/25189781
http://dx.doi.org/10.1093/bioinformatics/btu552