VSEAMS: a pipeline for variant set enrichment analysis using summary GWAS data identifies IKZF3, BATF and ESRRA as key transcription factors in type 1 diabetes

Motivation: Genome-wide association studies (GWAS) have identified many loci implicated in disease susceptibility. Integration of GWAS summary statistics (P-values) and functional genomic datasets should help to elucidate mechanisms. Results: We extended a non-parametric SNP set enrichment method to...

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Detalles Bibliográficos
Autores principales: Burren, Oliver S., Guo, Hui, Wallace, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296156/
https://www.ncbi.nlm.nih.gov/pubmed/25170024
http://dx.doi.org/10.1093/bioinformatics/btu571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296156/
https://www.ncbi.nlm.nih.gov/pubmed/25170024
http://dx.doi.org/10.1093/bioinformatics/btu571

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