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Essential roles of leucine-rich glioma inactivated 1 in the development of embryonic and postnatal cerebellum

Leucine-rich glioma inactivated 1 (LGI1) is a secreted protein that interacts with ADAM transmembrane proteins, and its mutations are linked to human epilepsy. The function of LGI1 in CNS development remains undefined. Here, we report novel functions of LGI1 in the generation of cerebellar granule p...

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Detalles Bibliográficos
Autores principales: Xie, Ya-Jun, Zhou, Liang, Jiang, Nanwei, Zhang, Nan, Zou, Na, Zhou, Lin, Wang, Yin, Cowell, John K., Shen, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296302/
https://www.ncbi.nlm.nih.gov/pubmed/25591666
http://dx.doi.org/10.1038/srep07827