P75 and phosphorylated c-Jun are differentially regulated in spinal motoneurons following axotomy in rats☆

The neurotrophin receptor (p75) activates the c-Jun N-terminal kinase (JNK) pathway. Activation of JNK and its substrate c-Jun can cause apoptosis. Here we evaluate the role of p75 in spinal motoneurons by comparing immunoreactivity for p75 and phosphorylated c-Jun (p-c-Jun), the production of JNK a...

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Detalles Bibliográficos
Autores principales: Yuan, Qiuju, Su, Huanxing, Wu, Wutian, Lin, Zhi-Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Research and Report Article: Spinal Cord Injury and Neural Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296419/
https://www.ncbi.nlm.nih.gov/pubmed/25624831
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.26.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296419/
https://www.ncbi.nlm.nih.gov/pubmed/25624831
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.26.001

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