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Developing an in vitro screening assay platform for evaluation of antifibrotic drugs using precision-cut liver slices
BACKGROUND: Precision-cut liver slices present different cell types of liver in a physiological context, and they have been explored as effective in vitro model systems to study liver fibrosis. Inducing fibrosis in the liver slices using toxicants like carbon tetrachloride is of less relevance to hu...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296550/ https://www.ncbi.nlm.nih.gov/pubmed/25598841 http://dx.doi.org/10.1186/s13069-014-0017-2 |