High-Speed AFM Images of Thermal Motion Provide Stiffness Map of Interfacial Membrane Protein Moieties

[Image: see text] The flexibilities of extracellular loops determine ligand binding and activation of membrane receptors. Arising from fluctuations in inter- and intraproteinaceous interactions, flexibility manifests in thermal motion. Here we demonstrate that quantitative flexibility values can be...

Descripción completa

Detalles Bibliográficos
Autores principales: Preiner, Johannes, Horner, Andreas, Karner, Andreas, Ollinger, Nicole, Siligan, Christine, Pohl, Peter, Hinterdorfer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296598/
https://www.ncbi.nlm.nih.gov/pubmed/25516527
http://dx.doi.org/10.1021/nl504478f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296598/
https://www.ncbi.nlm.nih.gov/pubmed/25516527
http://dx.doi.org/10.1021/nl504478f

Ejemplares similares