Soy polysaccharide as a novel superdisintegrant in sildenafil citrate sublingual tablets: preparation, characterization, and in vivo evaluation

Sildenafil citrate (SC), a drug used to treat erectile dysfunction, is available in tablet form but has three major problems. First, the drug displays inadequate aqueous solubility, which delays the onset of its action. Second, the drug undergoes extensive first-pass metabolism, resulting in a low (...

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Detalles Bibliográficos
Autores principales: Hosny, Khaled Mohamed, Mosli, Hisham Ahmed, Hassan, Ali Habiballah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296913/
https://www.ncbi.nlm.nih.gov/pubmed/25624751
http://dx.doi.org/10.2147/DDDT.S76314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296913/
https://www.ncbi.nlm.nih.gov/pubmed/25624751
http://dx.doi.org/10.2147/DDDT.S76314

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