Cargando…

A Cell-Targeted, Size-Photocontrollable, Nuclear-Uptake Nanodrug Delivery System for Drug-Resistant Cancer Therapy

[Image: see text] The development of multidrug resistance (MDR) has become an increasingly serious problem in cancer therapy. The cell-membrane overexpression of P-glycoprotein (P-gp), which can actively efflux various anticancer drugs from the cell, is a major mechanism of MDR. Nuclear-uptake nanod...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Liping, Chen, Tao, Öçsoy, Ismail, Yasun, Emir, Wu, Cuichen, Zhu, Guizhi, You, Mingxu, Han, Da, Jiang, Jianhui, Yu, Ruqin, Tan, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296921/
https://www.ncbi.nlm.nih.gov/pubmed/25479133
http://dx.doi.org/10.1021/nl503777s