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Warfarin Dosage Response Related Pharmacogenetics in Chinese Population

OBJECTIVES: As the most frequently prescribed anticoagulant, warfarin has large inter-individual variability in dosage. Genetic polymorphisms could largely explain the differences in dosage requirement. rs9923231 (VKORC1), rs7294 (VKORC1), rs1057910 (CYP2C9), rs2108622 (CYP4F2), and rs699664 (GGCX)...

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Detalles Bibliográficos
Autores principales: Li, Siyue, Zou, Yuangao, Wang, Xia, Huang, Xunbei, Sun, Yong, Wang, Yuqing, Dong, Li, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296935/
https://www.ncbi.nlm.nih.gov/pubmed/25594941
http://dx.doi.org/10.1371/journal.pone.0116463