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Microarray Analysis of Defective Cartilage in Hoxc8- and Hoxd4-Transgenic Mice
OBJECTIVE: Homeobox genes of the Hox class are required for proper patterning of skeletal elements and play a role in cartilage differentiation. In transgenic mice with overexpression of Hoxc8 and Hoxd4 during cartilage development, the authors observed severe defects, namely, physical instability o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297070/ https://www.ncbi.nlm.nih.gov/pubmed/26069554 http://dx.doi.org/10.1177/1947603510363005 |