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An In Vivo Lapine Model for Impact-Induced Injury and Osteoarthritic Degeneration of Articular Cartilage

OBJECTIVE: In this study, we applied a spring-loaded impactor to deliver traumatic forces to articular cartilage in vivo. Based on our recent finding that a 0.28-J impact induces maximal catabolic response in adult bovine articular cartilage in vitro using this device, we hypothesize that this impac...

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Detalles Bibliográficos
Autores principales: Alexander, Peter G., McCarron, Jesse A., Levine, Matthew J., Melvin, Gary M., Murray, Patrick J., Manner, Paul A., Tuan, Rocky S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297152/
https://www.ncbi.nlm.nih.gov/pubmed/26069642
http://dx.doi.org/10.1177/1947603512447301