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Antidepressant-like activity of magnesium in the olfactory bulbectomy model is associated with the AMPA/BDNF pathway

RATIONALE: Numerous studies suggest agents that act on glutamatergic transmission as potential antidepressants. Preclinical and clinical evidence suggests that magnesium, an N-methyl-d-aspartate receptor blocker, may be useful in the treatment of depression. OBJECTIVE: The aim of this study was to i...

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Detalles Bibliográficos
Autores principales: Pochwat, Bartlomiej, Sowa-Kucma, Magdalena, Kotarska, Katarzyna, Misztak, Paulina, Nowak, Gabriel, Szewczyk, Bernadeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297308/
https://www.ncbi.nlm.nih.gov/pubmed/25027582
http://dx.doi.org/10.1007/s00213-014-3671-6