Na(+) ions as spatial intracellular messengers for co-ordinating Ca(2+) signals during pH heterogeneity in cardiomyocytes

AIMS: Contraction of the heart is regulated by electrically evoked Ca(2+) transients (CaTs). H(+) ions, the end products of metabolism, modulate CaTs through direct interactions with Ca(2+)-handling proteins and via Na(+)-mediated coupling between acid-extruding proteins (e.g. Na(+)/H(+) exchange, N...

Descripción completa

Detalles Bibliográficos
Autores principales: Swietach, Pawel, Spitzer, Kenneth W., Vaughan-Jones, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297422/
https://www.ncbi.nlm.nih.gov/pubmed/25514933
http://dx.doi.org/10.1093/cvr/cvu251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297422/
https://www.ncbi.nlm.nih.gov/pubmed/25514933
http://dx.doi.org/10.1093/cvr/cvu251

Ejemplares similares