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Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice
BACKGROUND: Host-species specificity of the human immunodeficiency virus (HIV) limits pathobiologic, diagnostic and therapeutic research investigations to humans and non-human primates. The emergence of humanized mice as a model for viral infection of the nervous system has overcome such restriction...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297430/ https://www.ncbi.nlm.nih.gov/pubmed/25523827 http://dx.doi.org/10.1186/1750-1326-9-58 |