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Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice

BACKGROUND: Host-species specificity of the human immunodeficiency virus (HIV) limits pathobiologic, diagnostic and therapeutic research investigations to humans and non-human primates. The emergence of humanized mice as a model for viral infection of the nervous system has overcome such restriction...

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Detalles Bibliográficos
Autores principales: Boska, Michael D, Dash, Prasanta K, Knibbe, Jaclyn, Epstein, Adrian A, Akhter, Sidra P, Fields, Natasha, High, Robin, Makarov, Edward, Bonasera, Stephen, Gelbard, Harris A, Poluektova, Larisa Y, Gendelman, Howard E, Gorantla, Santhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297430/
https://www.ncbi.nlm.nih.gov/pubmed/25523827
http://dx.doi.org/10.1186/1750-1326-9-58