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Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice
BACKGROUND: Host-species specificity of the human immunodeficiency virus (HIV) limits pathobiologic, diagnostic and therapeutic research investigations to humans and non-human primates. The emergence of humanized mice as a model for viral infection of the nervous system has overcome such restriction...
Autores principales: | Boska, Michael D, Dash, Prasanta K, Knibbe, Jaclyn, Epstein, Adrian A, Akhter, Sidra P, Fields, Natasha, High, Robin, Makarov, Edward, Bonasera, Stephen, Gelbard, Harris A, Poluektova, Larisa Y, Gendelman, Howard E, Gorantla, Santhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297430/ https://www.ncbi.nlm.nih.gov/pubmed/25523827 http://dx.doi.org/10.1186/1750-1326-9-58 |
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