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miRNA-146 negatively regulates the production of pro-inflammatory cytokines via NF-κB signalling in human gingival fibroblasts

OBJECTIVE: In human gingival fibroblasts (HGFs), TLR4 recognises Pathogen-associated molecular patterns (PAMPs), such as LPS, and subsequently activates downstream signals that lead to the production of pro-inflammatory cytokines. The aim of this study was to explore the mechanisms of LPS-induced mi...

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Detalles Bibliográficos
Autores principales: Xie, Yu-feng, Shu, Rong, Jiang, Shao-yun, Song, Zhong-chen, Guo, Qiu-man, Dong, Jia-chen, Lin, Zhi-kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297434/
https://www.ncbi.nlm.nih.gov/pubmed/25598707
http://dx.doi.org/10.1186/s12950-014-0038-z