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miRNA-146 negatively regulates the production of pro-inflammatory cytokines via NF-κB signalling in human gingival fibroblasts
OBJECTIVE: In human gingival fibroblasts (HGFs), TLR4 recognises Pathogen-associated molecular patterns (PAMPs), such as LPS, and subsequently activates downstream signals that lead to the production of pro-inflammatory cytokines. The aim of this study was to explore the mechanisms of LPS-induced mi...
Autores principales: | Xie, Yu-feng, Shu, Rong, Jiang, Shao-yun, Song, Zhong-chen, Guo, Qiu-man, Dong, Jia-chen, Lin, Zhi-kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297434/ https://www.ncbi.nlm.nih.gov/pubmed/25598707 http://dx.doi.org/10.1186/s12950-014-0038-z |
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