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Sm16, a major component of Schistosoma mansoni cercarial excretory/secretory products, prevents macrophage classical activation and delays antigen processing

BACKGROUND: Schistosoma mansoni cercariae penetrate the skin by releasing excretory/secretory (E/S) products known as 0-3hRP, which are associated with immune modulation through Toll like receptor (TLR) signalling. Furthermore, these secretions contain Sm16, which when given to cells as a recombinan...

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Detalles Bibliográficos
Autores principales: Sanin, David E, Mountford, Adrian P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297449/
https://www.ncbi.nlm.nih.gov/pubmed/25561160
http://dx.doi.org/10.1186/s13071-014-0608-1