Genome-wide analysis of H3.3 dissociation reveals high nucleosome turnover at distal regulatory regions of embryonic stem cells

BACKGROUND: The histone variant H3.3 plays a critical role in maintaining the pluripotency of embryonic stem cells (ESCs) by regulating gene expression programs important for lineage specification. H3.3 is deposited by various chaperones at regulatory sites, gene bodies, and certain heterochromatic...

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Detalles Bibliográficos
Autores principales: Ha, Misook, Kraushaar, Daniel C, Zhao, Keji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297464/
https://www.ncbi.nlm.nih.gov/pubmed/25598842
http://dx.doi.org/10.1186/1756-8935-7-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297464/
https://www.ncbi.nlm.nih.gov/pubmed/25598842
http://dx.doi.org/10.1186/1756-8935-7-38

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