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SDF-1α/CXCR4 Axis Mediates The Migration of Mesenchymal Stem Cells to The Hypoxic-Ischemic Brain Lesion in A Rat Model

OBJECTIVE: Transplantation of mesenchymal stem cells (MSCs) can promote functional recovery of the brain after hypoxic-ischemic brain damage (HIBD). However, the mechanism regulating MSC migration to a hypoxic-ischemic lesion is poorly understood. Interaction between stromal cell-derived factor-1α (...

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Detalles Bibliográficos
Autores principales: Yu, Qin, Liu, Lizhen, Lin, Jie, Wang, Yan, Xuan, Xiaobo, Guo, Ying, Hu, Shaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297482/
https://www.ncbi.nlm.nih.gov/pubmed/25685734