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Tracing Dynamics and Clonal Heterogeneity of Cbx7-Induced Leukemic Stem Cells by Cellular Barcoding

Accurate monitoring of tumor dynamics and leukemic stem cell (LSC) heterogeneity is important for the development of personalized cancer therapies. In this study, we experimentally induced distinct types of leukemia in mice by enforced expression of Cbx7. Simultaneous cellular barcoding allowed for...

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Detalles Bibliográficos
Autores principales: Klauke, Karin, Broekhuis, Mathilde J.C., Weersing, Ellen, Dethmers-Ausema, Albertina, Ritsema, Martha, González, Marta Vilà, Zwart, Erik, Bystrykh, Leonid V., de Haan, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297865/
https://www.ncbi.nlm.nih.gov/pubmed/25434821
http://dx.doi.org/10.1016/j.stemcr.2014.10.012